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[12] Lastly, ALA may have mild anticoagulant effects (by enhancing blood flow and endothelial function), so combining it with anticoagulant or antiplatelet drugs could very slightly increase bleeding tendency

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91 In UC patients, endoplasmic reticulum function may be impaired, leading to abnormal accumulation of intracellular proteins and exacerbation of the cellular inflammatory response

Indeed NSAIDs, by virtue of their renown anti-inflammatory and antiplatelet (especially aspirin) activities could be beneficial for both the early control of inflammation and the prevention of thromboembolism, thus theoretically limiting COVID-19 progression in a bimodal pattern